The 10th International Conference on Information Security Practice and Experience (ISPEC 2014) was held in Fuzhou, China, during May 5-8, 2014. The conference was hosted by Fujian Provincial Key Laboratory of Network Security and Cryptology, Fujian Normal University. There were more than 120 peoples attending the conference. There were 36 papers accepted among 158 submissions. In conjunction with ISPEC 2014, there was a ''Huawei Information Security Practice and Experience Forum" sponsored by Huawei. The forum consisted of seven keynote speeches being delivered to the ISPEC 2014 participants. The topics of 36 presentations are of variety in system security, applied cryptography, network security and cryptanalysis.